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Product Information
General Properties of F-MELT®
F-MELT® is available in three grades, Type C, Type M, and F1.
- Grades
- Type C - Application: Pharmaceutical / Nutraceutical
- Type M - Application: Pharmaceutical
- F1 - Application: Nutraceutical/dietary supplement
Features
- Ready-to-use excipient for oral disintegrating tablets
- Directly compressible
- Oral disintegrating time less than 30 seconds
- Tablet hardness more than 50 Newtons
- API loading more than 50% possible
- Highly flowable with minimum or no sticking/capping
- Suitable with conventional tabletting machines
- No Royalty or license fee required
Physical Properties of F-MELT®
(Empirical)
Scanning Electron Micrographs
F-MELT® co-spray dried powder (X 500)
F-MELT® co-spray dried powder (X 10,000)
Performance of F-MELT placebo tablets
- F-MELT® Type C, Type M
- Formulation: F-MELT® 99.5% ＋ Mg-St 0.5% (Dry Blending)
- Tablet Size: ø11.3 mm, 450 mg / Tab
- Tablet Machine: Tabletting Tester SK-02 (Sankyo Piotech)
- The tablet hardness shows a linear increment up to 1 ton compression force
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Tablet Hardness vs Oral Disintegration time (Placebo)
- Excipient: F-MELT® Type C, M
- Formulation: F-MELT® 99.6% ＋ Mg-St 0.4%
- Conditions: 20 rpm, φ8 mm, 200 mg Tab
- Tabletting after blending F-MELT® with Lubricant
- Excipient: F-MELT® F1
- Formulation: F-MELT® 99.5%
- Lubricant: Sucrose Esters S-370F
- Tablet Size: ø8 mm x 9R, 200 mg/Tab, 15 rpm
Maintain optimum disintegration time at higher tablet hardness
Friability decreases rapidly with increased tablet hardness
Moisture Sorption Isotherm (25°C, 7days)
F-MELT® Type M
F-MELT® Type C
Package Size
- a) Commercial Size:
- 20 kg net in aluminum bag in carton box
- Box dimension: 880 mm x 990 mm
- b) Sample Size:
- 1 kg net in aluminum bag
- Bag dimension: 220 mm x 334 mm x c.a 50 mm
- c) Placebo tablets are also available as sample
